Types of Brain Cancer and Prognosis
Sunday, September 23, 2018
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types of brain cancer and prognosis via aans.org |
Hello I'm dr. Matt Yuen I'm the chairman of neurosurgery at the University of North Carolina and the director of the brain tumor program at the UNC Lineberger Comprehensive Cancer
Center today I'd like to talk with you about brain cancer or brain tumors particularly we'd like
to focus on tumors that start in the brain often called primary brain tumors or gliomas today
we're gonna talk about brain cancer or brain tumors there's several different types of brain
tumors and it's an important from the beginning to understand whether the tumor we're
discussing started in the brain we call that a primary brain tumor and the most common form
of that is a glioma or if the tumor spread to the brain from somewhere else and we call that a
metastatic brain tumor those often spread from other types of cancer like lung cancer breast
cancer or melanoma however any sort of tumor can spread to the brain this video is going to
focus on tumors that started in the brain rather than those that spread from somewhere else
we'll have a separate presentation available to talk about the metastatic brain tumors now
there are about 75,000 primary brain tumors a year in the United States that's approximately
25 to murrs for every hundred thousand people about one-third of those tumors are
malignant or cancerous tumors unfortunately about two-thirds of the tumors are benign
tumors again today I want to focus my comments on the cancerous or malignant brain tumors
as a doctor who treats patients with malignant brain tumors I'm interested when I meet a new
patient to learn many things about them and then about their tumor the most important
things for me to know about their tumor are the grade of the tumor and the type of the tooth
so let me explain that in a little more detail we traditionally grade the tumors on a scale of
one to four and the grade one tumors are the lowest and the grade four are the most aggressive
in general the grade of the tumor tends to track with the age of the patient so younger
patients in their teens or 20s are more likely to have a great one tumor the grade two tumors
tend to occur in the 20s and 30s and the grade three and four tumors tend to happen in
people who are older grade is certainly a very important thing to to know about a patient in
their tumor when we're deciding on treatment and trying to give the patient information
about the tumor the other important thing to know is the type of tumor there are two main
types of tumors that occur in the brain the first are Astro CITIC tumors that's one type of
tumor in cell brain the astrocytes and the other are oligodendroglioma that's a couple of big
words that even I struggle with and so we frequently call these the A's and the O's the
astrocytes and the oligodendrocytes and those two types of cells are just cells that support the
tissue in the brain the most important cells of the brain are the neurons that's what makes us
think and run and be ourselves but those neurons need help from other cells and those cells are
called the glia and the astrocytes and the oligodendrocytes are just members of that gweal
family so for every patient I meet once I get to know them and learn about their story I want
to know about their tumor what's the number great and then what is the letter the a or the o
that goes with this in general the lower the number and the more O in the tumor the better we
are so a grade 2o tumor at the outset would be easier to treat than a grade 4 a 2 now the
naming of brain tumors can get very confusing very quickly but there probably a couple other
terms that would be useful for you to know as you learn about brain tumors grade 4 tumors are
often called glioblastoma or abbreviated GBM and so the grade 4 tumor are the GBM is the
most aggressive tumor and the low-grade tumor the grade 2 tumor would be the least
aggressive tumor from the spectrum of grade 2 3 4 tumors we've talked about a number of
different kinds of brain tumors from these primary brain tumors that can be grade two tumors
grade 3 grade 4 and can start from either the astrocytes which are the o the A's or they're all
the tender sites which are the O's all of these tumors regardless of the grade or the type of cell
have treatment options and modalities that can be used to stop their growth some can be
removed others are treated with chemotherapy some are treated with radiation and many
receive a combination of this regardless of what type of tumor you or your family member or
friend has there's likely to be very good treatment options available to them and we'll get into that in just a minute.
Types of brain cancer and prognosis
Let's talk for a moment about the prognosis for patients diagnosed with brain tumors and once
we get through the first round of therapy of surgery and radiation chemotherapy what you can
expect to come in the months and years that lay ahead in general the diagnosis of brain
cancer is one that will need to stay active in your medical care the rest of your life by that I
mean that you'll have a team of doctors or a particular doctor who you identify as your brain
tumor doctor who will be following this they'll be in charge of ordering the appropriate scans
modifying their therapy counseling you about what the appropriate treatment is in patients
who are doing very well this may just be a series of MRI scans in patients whose tumor has
progressed or grown it may mean changing therapies either to a different form of the same
therapy a new chemo therapy or going back to radiation or surgery in a follow-up mode at
any point when the tumor starts to grow we revisit all of the treatment options the other
important thing to be asking your physician is to make sure that they're constantly looking
for new treatments that are available we have things available to treat patients today that
weren't routinely used three or five years ago we want to make sure that everybody's
treatment is based on the most available is based on the most current data and incorporates all of new treatment options. Next Types of Brain Cancer and Survival Rate
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